Modelling synergistic action of laccase-based biosensor utilizing simultaneous substrates conversion |
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Authors: | Evelina Gaidamauskaitė Romas Baronas Juozas Kulys |
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Institution: | (1) Dept. Mathematics & Informatics, Vilnius University, Naugarduko 24, LT-03225 Vilnius, Lithuania;(2) Dept. Chemistry & Bioengineering, Vilnius Gediminas Technical University, Sauletekio Ave. 11, LT-10223 Vilnius, Lithuania; |
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Abstract: | The response of a laccase-based amperometric biosensor that acts in a synergistic manner was modelled digitally. A mathematical
model of the biosensor is based on a system of non-linear reaction diffusion equations. The modelling biosensor comprises
three compartments, an enzyme layer, a dialysis membrane and an outer diffusion layer. By changing input parameters the biosensor
action was analysed with a special emphasis to the influence of the species concentrations on the synergy of the simultaneous
substrates conversion. The digital simulation was carried out using the finite difference technique. |
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Keywords: | |
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