Sugar sensing based on induced pH changes |
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| Authors: | Kim Youngmi Hilderbrand Scott A Weissleder Ralph Tung Ching-Hsuan |
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| Affiliation: | Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA. |
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| Abstract: | A sensory assembly consisting of a pH sensitive NIR dye and an arylboronic acid shows ratiometric absorption changes with increased fluorescence intensity upon addition of sugar in aqueous media; this demonstrates a new signal transduction mechanism for the detection of sugar based on pH changes induced in the microenvironment of the sensory assembly. |
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