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APPLICATION OF SURFACE GRAFTED POLY N-ISOPROPYL ACRYLAMIDE BY RADIATION TECHNOLOGY FOR PROTEIN SOLUTION CONCENTRATION
引用本文:孙以实,李怀忠,刘鹏飞,哈鸿飞. APPLICATION OF SURFACE GRAFTED POLY N-ISOPROPYL ACRYLAMIDE BY RADIATION TECHNOLOGY FOR PROTEIN SOLUTION CONCENTRATION[J]. 高分子科学, 1991, 0(4): 353-357
作者姓名:孙以实  李怀忠  刘鹏飞  哈鸿飞
作者单位:Tsinghua University,Beijing,Tsinghua University,Beijing,Peking University,Beijing,Peking University,Beijing
基金项目:This project is sponsored by the National Natural Science Foundation of China.
摘    要:Poly N-isopropyl acrylamide (abbreviated as PNIPA) as a kind of thermally sensitive hydrogel is utilized to concentrate Bovin Serum Albumin (BSA) solution. In order to decrease its surface adsorption to BSA in aqueous solution, surface layer grafting of the gels by radiation technology was carried out. The results showed that hydroxyl propyl methacrylate (HPMA) grained gel exhibited a low level of BSA adsorption and still kept the original thermally sensitive properties of PNIPA hydrogels.

收稿时间:1990-12-20

APPLICATION OF SURFACE GRAFTED POLY N-ISOPROPYL ACRYLAMIDE BY RADIATION TECHNOLOGY FOR PROTEIN SOLUTION CONCENTRATION*
SUN Yishi,LI Huaizhong,LIU Pengfei,HA Hongfei. APPLICATION OF SURFACE GRAFTED POLY N-ISOPROPYL ACRYLAMIDE BY RADIATION TECHNOLOGY FOR PROTEIN SOLUTION CONCENTRATION*[J]. Chinese Journal of Polymer Science, 1991, 0(4): 353-357
Authors:SUN Yishi  LI Huaizhong  LIU Pengfei  HA Hongfei
Affiliation:Tsinghua University; Beijing; Peking University
Abstract:Poly N-isopropyl acrylamide (abbreviated as PNIPA) as a kind of thermally sensitive hydrogel is utilized to concentrate Bovin Serum Albumin (BSA) solution. In order to decrease its surface adsorption to BSA in aqueous solution, surface layer grafting of the gels by radiation technology was carried out. The results showed that hydroxyl propyl methacrylate (HPMA) grained gel exhibited a low level of BSA adsorption and still kept the original thermally sensitive properties of PNIPA hydrogels.
Keywords:Poly N-isopropylacrylamide  hydroxyl propyl methacrylate  Boving serum albumin  thermally sensitive hydrogel  radiation   surface grafting
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