Facile total synthesis of xanthorrhizol |
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| Authors: | Du Zhenting Wang Yin Ma Weili Lv Dong Yu Hongrui |
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| Institution: | College of Science, Northwest A&F University, Yangling, Shaanxi, 712100, China. duzt@nwsuafedu.cn |
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| Abstract: | A facile total synthesis of the bisabolane sesquiterpene, xanthorrhizol (1), has been achieved in 6 steps, in 48% overall yield. The starting material was 3-methoxy-4-methyl-phenoacetone (7), and a Claisen-Johnson rearrangement was used as the key step to construct the skeleton of the target molecule. |
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