Chemical constituents and antioxidant activity of Ficus callosa |
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Authors: | Van Kiem Phan Cuong Nguyen Xuan Nhiem Nguyen Xuan Hang Dan Thi Thuy Nam Nguyen Hoai Ban Ninh Khac Minh Chau Van Bing Zhou Jang Hae Dong Kim Young Ho |
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Affiliation: | Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Vietnam. phankiem@vast.ac.vn |
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Abstract: | One new megastigmane glycoside, ficalloside (1), and eleven known compounds, were isolated from methanol extract of Ficus callosa leaves by repeated column chromatography. Their structures were established on the basis of spectral and chemical evidence. The antioxidant activities of these compounds were measured using the oxygen radical absorbance capacity (ORAC) assay. Compound 8 exhibited potent antioxidant activity of 10.6 microM trolox equivalents at the concentration of 2 microM. At this concentration, compounds 4-7 and 9-12 showed significant antioxidant activity with ranging of 2.1-6.1 microM trolox equivalents. |
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