DBU-Mediated Carboxylative Coupling of Primary Amines,Carbon Dioxide and Propargyl Chlorides

A carboxylative coupling reaction of various primary amine and 3‐phenyl‐2‐propynyl or 2‐nonynyl chloride in the presence of 8‐diazabicyclo5.4.0]undec‐7‐ene (DBU) using carbon dioxide as carboxylative reagent was presented. This transition‐metal free reaction system shows broad substrate scope and gives a series of propargylcarbamates in moderate to good yield. The obtained N‐alkyl substituted carbamate product can undergo base‐catalyzed intramolecular cyclization reaction to afford functionalized 4‐methylene‐2‐oxazolidinone in good yield.