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Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety
Authors:N M Khalifa  E S Nossier  M A Al-Omar  A E Amr
Abstract:3-Aryl-5-(Z)-pyrenylmethylene]-2-alkylthiohydantoins and 3-Aryl-5-(Z)-pyrenylmethylene]-2-(D-glycosyl)-2-thiohydantoins functionalized with different aromatic and glycoside substituents have been synthesized by the reaction of (Z)-3-(4-methoxyphenyl)-5-(pyren-8-yl)methylene]-2-thiohydantoin with alkyl halides, cyclic and acyclic nucleosides via various routes with moderate to good yields and characterized by 1H, 13C NMR and mass spectra and elemental analysis
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