| Facile Synthesis and Adsorption Properties of Phosphonated Cellulose Beads for Selective Removal of Low-density Lipoprotein |
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| 作者姓名： | Hao Feng YU Guo Qi FU Li LIU Bing Lin HE |
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| 作者单位： | Hao Feng YU，Guo Qi FU，Li LIU，Bing Lin HE The Key Laboratory of Functional Polymer Materials of Ministry of Education，Institute of Polymer Chemistry，Nankai University，Tianjin 300071 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | Hyperlipemia, which induced by the abnormally elevated level of lipids in plasma such as cholesterol and triglyceride (TG), now has been widely recognized as a major risk factor of coronary heart disease1. Low-density lipoprotein (LDL) particles are the m…
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| 关 键 词： | 纤维素 磷酸化作用 低密度脂蛋白 吸附 高脂血 |
| 收稿时间： | 2006-04-03 |
Facile Synthesis and Adsorption Properties of Phosphonated Cellulose Beads for Selective Removal of Low-density Lipoprotein |
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| Hao Feng YU Guo Qi FU Li LIU Bing Lin HE.Facile Synthesis and Adsorption Properties of Phosphonated Cellulose Beads for Selective Removal of Low-density Lipoprotein[J].Chinese Chemical Letters,2006,17(9):1193-1196. |
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| Authors: | Hao Feng YU Guo Qi FU Li LIU Bing Lin HE |
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| Abstract: | A novel low-density lipoprotein adsorbent was prepared simply by directly phosphonating porous cellulose beads. Tests in vitro demonstrated that this adsorbent showed quite good adsorption performance for selective removal of low-density lipoprotein from human plasma. The effects of preparation conditions on the lipoprotein sorption properties of the resulted adsorbent were investigated. The adsorption dynamics was also examined. |
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| Keywords: | Cellulose beads phosphonation low-density lipoprotein adsorption hyperlipemia |
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