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Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates
Authors:Fauzia Izzati  Mega Ferdina Warsito  Asep Bayu  Anggia Prasetyoputri  Akhirta Atikana  Linda Sukmarini  Siti Irma Rahmawati  Masteria Yunovilsa Putra
Affiliation:Research Center for Biotechnology, Indonesian Institute of Sciences, Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor, West Java 16911, Indonesia or (F.I.); (M.F.W.); (A.P.); (A.A.); (L.S.); (S.I.R.)
Abstract:Marine invertebrates have been reported to be an excellent resource of many novel bioactive compounds. Studies reported that Indonesia has remarkable yet underexplored marine natural products, with a high chemical diversity and a broad spectrum of biological activities. This review discusses recent updates on the exploration of marine natural products from Indonesian marine invertebrates (i.e., sponges, tunicates, and soft corals) throughout 2007–2020. This paper summarizes the structural diversity and biological function of the bioactive compounds isolated from Indonesian marine invertebrates as antimicrobial, antifungal, anticancer, and antiviral, while also presenting the opportunity for further investigation of novel compounds derived from Indonesian marine invertebrates.
Keywords:Indonesia   marine natural product   marine invertebrates   soft corals   sponges   tunicates   biodiversity   biological activity
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