Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates |
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Authors: | Fauzia Izzati Mega Ferdina Warsito Asep Bayu Anggia Prasetyoputri Akhirta Atikana Linda Sukmarini Siti Irma Rahmawati Masteria Yunovilsa Putra |
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Affiliation: | Research Center for Biotechnology, Indonesian Institute of Sciences, Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor, West Java 16911, Indonesia or (F.I.); (M.F.W.); (A.P.); (A.A.); (L.S.); (S.I.R.) |
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Abstract: | Marine invertebrates have been reported to be an excellent resource of many novel bioactive compounds. Studies reported that Indonesia has remarkable yet underexplored marine natural products, with a high chemical diversity and a broad spectrum of biological activities. This review discusses recent updates on the exploration of marine natural products from Indonesian marine invertebrates (i.e., sponges, tunicates, and soft corals) throughout 2007–2020. This paper summarizes the structural diversity and biological function of the bioactive compounds isolated from Indonesian marine invertebrates as antimicrobial, antifungal, anticancer, and antiviral, while also presenting the opportunity for further investigation of novel compounds derived from Indonesian marine invertebrates. |
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Keywords: | Indonesia marine natural product marine invertebrates soft corals sponges tunicates biodiversity biological activity |
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