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Screening of acetogenin-producing plants in Brazilian flora |
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| Authors: | Fontana José D. Almeida Eduardo R. A. Baron Madalena Guimaraes Manoel F. Deschamps Francisco C. Schwartsmann Gllberto Cervi Armando C. Zanette Flávio Vilegas Janete LanÇas Fernando M. |
| Affiliation: | 1.UFPR, Federal University of Parana, PO Box 19046, 81531-970, CURITIBA, PR, Brazil ;2.LQBB-Biomass Chemo/Biotechnology Laboratory, Federal University of Rio Grande do Sul, Brazil ;4.Botany, Federal University of Rio Grande do Sul, Brazil ;5.Agriculture/Phytosanitarism, Federal University of Rio Grande do Sul, Brazil ;3.UFRS, Federal University of Rio Grande do Sul, Brazil ;6.USP/SC, LabChro, University of Sāo Paulo, campus Sāo Carlos, Brazil ; |
| Abstract: | The acetogenins are strongly bioactive natural compounds present in the bark, roots, leaves, and seeds of manyAnnonaceae plants. They are modified fatty acids and their cytotoxicities have been determined for different biological models including the in vitro growth inhibition of several human cancer cell lines. Very low acetogenin yield (< 0.1 g%) has been found previously in native phytobiomass, and we have now investigated the nonpredatory exploitation of the seeds as acetogenin sources characterizing the seed triacylglycerols (dominant fraction; > 90% of the whole lipid extracts) as potential valuable by-products. |
| Keywords: | KeywordHeading" >Index Entries Acetogenins Annonaceae seed oil tetrahydrofuranoid fatty acid lactones Annona Rollinia polyketides |
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