利用血管回声跟踪技术研究老年人类风湿关节炎与动脉弹性的相关性

为了给早期预防和治疗心血管疾病提供参考,利用血管回声跟踪技术研究老年人类风湿关节炎与动脉弹性的相关性。研究对象选择年龄在60～79岁之间的老年人类风湿关节炎患者40例和健康老年人40例,依次作为实验组与对照组。采用ALOKA Prosoundα10.型彩色超声诊断仪对颈动脉和肱动脉内中膜厚度以及弹性相关参数进行检测。结果发现:检测结果中有35例类风湿关节炎患者颈动脉IMT值超过1 mm,有31例健康研究对象颈动脉IMT值超过1 mm;实验组颈动脉IMT和对照组相比差异无统计学意义(p 0. 05),β、Ep、PWVβ和AI与对照组相比差异有统计学意义(p 0. 05,p 0. 01);实验组与对照组的肱动脉IMT值间无显著差异(p 0. 05),β、PWVβ与AI间有显著性差异(p 0. 05); ROC曲线分析结果中,两组研究对象动脉弹性参数差异有统计学意义(p 0. 05)。可见类风湿关节炎与老年人颈动脉和肱动脉弹性存在显著相关性,但受年龄的影响,动脉IMT值改变无法体现RA和动脉粥样硬化在统计学上的相关性,根据实验结果可知,可将ET技术当成一种早期发现RA患者动脉弹性功能下降的诊断方法预防心血管疾病。

Study on the Correlation between Rheumatoid Arthritis and Arterial Elasticity in the Elderly by Echo Tracking Technique

In order to provide reference for early prevention and treatment of cardiovascular diseases, the correlation between rheumatoid arthritis and arterial elasticity in the elderly was studied by using echo tracking technique. Objectives 40 elderly patients with rheumatoid arthritis and 40 healthy elderly people aged 60 to 79 were selected as experimental group and control group. The intima-media thickness and elasticity parameters of carotid and brachial arteries were measured by ALOKA Prosound alpha 10. The results showed that the IMT value of carotid artery was more than 1 mm in 35 patients with rheumatoid arthritis and more than 1 mm in 31 healthy subjects. There was no significant difference between the experimental group and the control group (p > 0.05). There were significant differences in the IMT value of brachial artery between the experimental group and the control group (p < 0.05, P < 0.01). There were significant differences between the two groups (p > 0.05), and there were significant differences between the two groups (p < 0.05). The results of ROC curve analysis showed that there were significant differences in the parameters of arterial elasticity between the two groups (p < 0.05). It can be seen that there is a significant correlation between rheumatoid arthritis and the elasticity of carotid and brachial arteries in the elderly. However, due to the influence of age, the change of IMT value of arteries can not reflect the statistical correlation between RA and atherosclerosis. According to the experimental results, ET technology can be used as an early diagnostic method to detect the decline of arterial elasticity in RA patients to prevent cardiovascular diseases.