One-pot inversion of d-mannono-1,4-lactone for the practical synthesis of l-ribose |
| |
| Authors: | Myung Joon SeoJoungho An Jae Hak ShimGuncheol Kim |
| |
| Affiliation: | a HanChem Co., Ltd, Jeonmin Dong, Yusung Gu, Daejeon 305-390, Republic of Korea
b Department of Chemistry, College of Natural Sciences, Chungnam National University, Daejon 305-764, Republic of Korea |
| |
| Abstract: | l-Ribose was synthesized in a concise manner from d-mannono-1,4-lactone using one-pot inversion conditions. Treatment of d-mannono-1,4-lactone with piperidine, followed by mesylation-induced SN2-type O-alkylation, afforded the desired one-pot inversion in an optimum yield, and the following straightforward transformations provided l-ribose in good yields. |
| |
| Keywords: | smallcaps" >l-ribose inversion smallcaps" >d-mannono-1,4-lactone |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
