|
|||||
|
|
Polymer-supported electron-rich diene for hetero Diels-Alder reactions |
|
| Authors: | Camille PierresPascal George,Luc van Hijfte,Jean-Bernard DucepMarcel Hibert,André Mann |
| Affiliation: | a Laboratoire de Pharmacochimie de la Communication Cellulaire, UMR 7081, Faculté de Pharmacie, 74, route du Rhin, F-67401 Illkirch, France b Département de Recherche SNC Laboratoire de Recherche Sanofi-Synthelabo, 31 av. P. V. Couturier, F-92220 Bagneux, France c Sanofi-Synthelabo Recherche, Département de Recherche Exploratoire, 16, rue d'Ankara, F-67000 Strasbourg, France |
| Abstract: | A Brassard diene analogue was grafted on a modified Merrifield resin and used in a hetero Diels-Alder reaction with various aldehydes or ketones. The reaction gave access to 6-substituted 5,6-dihydropyrones (5a-u). This new immobilized electron-rich diene is more stable than the corresponding native diene, and is a versatile supported reagent. |
| Keywords: | solid supported reagent hetero Diels-Alder 5,6-dihydropyrones |
| 本文献已被 ScienceDirect 等数据库收录！ | |