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An efficient synthesis of novel deoxy phospha sugar pyrimidine nucleosides |
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| Authors: | Mitsuji Yamashita Valluru Krishna ReddyPutta Mallikarjuna Reddy Yukihiro KatoBuchammagari Haritha Kazumitsu SuzukiMasaki Takahashi Tatsuo Oshikawa |
| Institution: | a Department of Materials Chemistry, Faculty of Engineering, Shizuoka University, Hamamatsu 432-8561, Japan b Satellite Venture Business Laboratory, Shizuoka University, Hamamatsu 432-8561, Japan c Graduate School of Science and Engineering, Shizuoka University, Hamamatsu 432-8561, Japan d Department of Chemistry and Biochemistry, Numazu College of Technology, Numazu 410-8501, Japan |
| Abstract: | An efficient method is described in the synthesis of several novel deoxy phospha sugar pyrimidine nucleosides in racemic form, analogs of normal sugar nucleosides, in high yields by treatment of (±)-2-aminophospholane 1-oxide with several, α-cyano-, -acetyl-, -ethoxycarbonyl-β-ethoxy-N-ethoxycarbonylacrylamides. |
| Keywords: | phospha sugars hetero sugars phospha sugar nucleosides aminophospholanes |
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