Studies on uracils: synthesis of novel pyrido[2,3-d]pyrimidine oxides via ring transformation of isoxazolo[3,4-d]pyrimidine |
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| Authors: | P.J Bhuyan H.N BorahR.C Boruah |
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| Affiliation: | Medicinal Chemistry Division, Regional Research Laboratory, Jorhat 785006, Assam, India |
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| Abstract: | The reaction of isoxazolo[3,4-d]pyrimidine 1 and cyanoolefins 2 in the presence of triethylamine (Et3N) as a catalyst afforded an unprecedented one-pot synthesis of biologically important pyrido[2,3-d]pyrimidine oxides 3 in excellent yields. |
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| Keywords: | uracil cyanoolefins pyrido[2,3-d]pyrimidines |
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