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Cu(OTf)2: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones |
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| Authors: | A.S. ParaskarG.K. Dewkar A. Sudalai |
| Affiliation: | Process Development Division, National Chemical Laboratory, Pashan Road, Pune 411008, India |
| Abstract: | Copper(II) triflate catalyzes efficiently the three-component condensation reaction of an aldehyde, β-ketoester and urea in acetonitrile to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in high yields. The catalyst exhibited remarkable reusable activity. |
| Keywords: | aldehydes Biginelli reactions catalysts 3,4-dihydropyrimidin-2(1H)-ones copper and compounds |
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