Novel indium-mediated ternary reactions between indole-3-carboxaldehydes-allyl bromide-enamines: facile synthesis of bisindolyl- and indolyl-heterocyclic alkanes |
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| Authors: | Subodh Kumar Vijay KumarSwapandeep Singh Chimni |
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| Institution: | Department of Chemistry, Guru Nanak Dev University, Amritsar 143 005, India |
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| Abstract: | Indole-3-carboxaldehydes undergo indium-mediated ternary reactions with allyl bromide and indoles to provide symmetrical and unsymmetrical bisindolyl alkanes and with other heterocyclic enamines viz. pyrrole, pyrazole, 6-aminouracil and imidazole to provide indolyl-heterocyclic alkanes in excellent yields. The reactions with substituted allyl bromides proceed with greater ease. |
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