A new route towards N-(α-methoxybenzyl)aziridines |
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| Authors: | Matthias D'hoogheArn Hofkens Norbert De Kimpe |
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| Affiliation: | Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium |
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| Abstract: | A new synthesis of N-(α-methoxyarylmethyl)-2,2-dimethylaziridines is presented. Different benzaldehydes were converted into the corresponding imines upon reaction with 2-bromo-2-methylpropylamine. Treatment of the latter imines with sodium methoxide afforded N-(α-methoxyarylmethyl)-2,2-dimethylaziridines in good yields. |
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| Keywords: | aziridines β-haloamines aldimines |
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