Synthesis of hydroxy-substituted unsaturated fatty acids and the amino-acid insect-derivative volicitin |
| |
Authors: | Han-Xun WeiChristopher L Truitt Paul W Paré |
| |
Institution: | Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA |
| |
Abstract: | An efficient synthesis of N-(17S-hydroxylinolenoyl)-l-glutamine (volicitin), a chemical elicitor from the herbivore-pest beet armyworm is presented. The synthesis, which utilizes a copper-catalyzed acetylene coupling, links (S)-3,6-heptadiyne-2-ol with a C-8 propargylic iodine methyl ester to form the (S)-17-hydroxylinolenate skeleton. By substituting different heptadiyne-2-ol groups, a series of methylene interrupted polyacetylene analogues were generated. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|