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| Reactivity of C-10 Function in Sinenxan A and Its Derivatives | |
| 摘 要： | SinenxanA(1)isabioSynheticallyavailallletaxoidI'1ComParedwiththehaousanticanceragentPaClitaxel(taxol',2)2],themOStconSPicuouschrencebebenthesetW0co~dsinthelocallonOfOxygnnfunchonsisl4P-0AcinthefOrmerandl3a-0C0Rinthelatter.Wththeaimof~ningnewanhcanceragents,wewereinterestedinInakingchendcalmedCationsonsinenxanAincluding,amongothers,theconSructon0ftheoxetanering'],andtheattaChmentOfanisoserine-twsidechainatl4-positionasadricryOf2.InthecourseOfitSforcturaJm~CatioftweboserVedthaitSC-… |
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