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Production and hydrolysis of 3,4-dimethyl-2,5-diphenyl-1,3-oxazolidine
Authors:Martina Astrová  Ladislav Kurc and Libor &#;erveny
Institution:(1) Department of Organic Technology, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic;(2) Department of Organic Technology, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic;(3) Department of Organic Technology, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic
Abstract:Summary Condensation of ephedrine with benzaldehyde, an acid catalyzed reversible reaction, producing 3,4-dimethyl-2,5-diphenyl-1,3-oxazolidine, was studied. If the starting reaction mixture contained acetic acid, it quantitatively reacted with ephedrine and produced a salt functioning as an acid catalyst. On the contrary, ephedrine hydrochloride had no catalytic effect.
Keywords:hydrolysis  Ephedrine  condensation  oxazolidine
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