Stereoselective total synthesis of (+)-mueggelone, a novel inhibitor of fish development |
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Authors: | J.S. Yadav R. Somaiah K. Ravindar L. Chandraiah |
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Affiliation: | Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
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Abstract: | An efficient stereoselective total synthesis of (+)-mueggelone, a novel inhibitor of fish development, is described. Highlights of the strategy include the utilization of Sharpless asymmetric epoxidation, Yamaguchi lactonization and an olefin cross-metathesis as the key steps. |
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