Synthesis and structure of 1-(2-amino)phenyl-2-phenyl-12H-indolo[3,2-c]carbazole ethylacetate solvate,a new indolocarbazole compound

The structure of a new indolo-carbazole compound, unique in having two indole rings with NH groupstrans-fused to a phenyl ring, has been determined by X-ray crystallography. The crystals are monoclinic, space groupP2₁/n,a=25.548(7),b=8.532(3),c=12.594(4) Å,=93.50(2)°,V _c=2740.1(2) ų,Z=4,D _k=1.240 g cm^–3, (CuK)=1.54178 Å,=5.79 cm^–1,F(000)=1080,R=0.071,R _w=0.080 for 2939 unique significant reflections measured at 298 K. The crystals retain one mole of ethyl acetate per molecule, which shows disorder. Restricted rotation of the phenyl and aminophenyl groups was detected by¹³C nmr. The title Indolo-carbazoles are easily obtained by reaction of 3-bromoindoles with 2,3-biindolyls and show an interesting planar structure which could be investigated for anticancer properties.