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Syntheses, Characterization and Equilibrium between Mono-and Aqua-bridged Dicobalt(II) Complexes. A Structural Model for Methionine Aminopeptidase
引用本文:叶保辉,陈小明. Syntheses, Characterization and Equilibrium between Mono-and Aqua-bridged Dicobalt(II) Complexes. A Structural Model for Methionine Aminopeptidase[J]. 中国化学, 2003, 0(5)
作者姓名:叶保辉  陈小明
作者单位:School of Chemistry and Chemical Engineering,Sun Yat Sen University,Guangzhou,Guangdong 510275,China,School of Chemistry and Chemical Engineering,Sun Yat Sen University,Guangzhou,Guangdong 510275,China
基金项目:ProjectsupportedbyNaturalScienceFoundationofGuangdongProvinceandtheMinistryofEducationforreturnedscientistsfromabroad .
摘    要:IntroductionIthasbeenfoundfrequentlyinhydrolasesthattwoormoremetalionsareassembledinverycloseproximitytothecarboxylatesidechainsofaminoacidresiduesatenzymeac tivesitestocarryouttheirbiologicalfunctions.1Metalsem ployedinhydrolasesincludemagnesium ,manganese ,iron ,cobalt,nickelandzinc .1Onekindofhydrolases,themethio nineaminopeptidasefromE .coil (EcMAP) 2 andPyrococcusfuriosus (PfMAP) 3bothrequiretwoCo2 + ionsfortheiractiv ity ,whereastheirstructuresaredifferent.Thediversestructuresandmet…


Syntheses, Characterization and Equilibrium between Mono-and Aqua-bridged Dicobalt(II) Complexes. A Structural Model for Methionine Aminopeptidase
Abstract:
Keywords:synthesis   cobalt(II) complex   dinuclear   hydrolase
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