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Synthesis of analogs of ecdysteroids containing an isoxaline ring in the side chain
Authors:R. P. Litvinovskaya  S. V. Drach  G. A. Zhilitskaya  V. A. Khripach
Affiliation:(1) Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, 220141, Belarus
Abstract:Starting with poststerone a synthesis was performed of ecdysteroid analogs containing an isoxaline ring in the side chain. The key stages of the route to the target products were Normant reaction and the subsequent 1,3-dipolar cycloaddition of nitrile oxides to 20-hydroxy-20-vinylsteroids.
Keywords:
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