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Facile synthesis of 3-substituted thieno[3,2-b]furan derivatives
Authors:Noé  mie Hergué  
Affiliation:Université d’Angers, CNRS, Laboratoire de Chimie et Ingénierie Moléculaire d’Angers, CIMA UMR 6200, Groupe SCL, 2 Boulevard Lavoisier, 49045 Angers, France
Abstract:A facile synthesis of dimethyl 3-hydroxythieno[3,2-b]furan-2,5-dicarboxylate is reported from the available methyl thioglycolate and dimethyl acetylenedicarboxylate starting materials. This compound represents an efficient precursor for the synthesis of 3-substituted thieno[3,2-b]furan derivatives.
Keywords:Furan   Thienofuran   Dieckmann cyclization   Heterocyclic chemistry
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