A GSH-responsive PET-based fluorescent probe for cancer cells imaging |
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Authors: | Xue Li Huaying Wang Youhui Zhang Qianyong Cao Yong Chen |
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Institution: | 1. Chemical College, Nanchang University, Nanchang 330031, China;2. Jiangxi Key Laboratory for Microscale Interdisciplinary Study, Institute for Advanced Study, Nanchang University, Nanchang 330031, China |
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Abstract: | An efficient PET-based probe, in which the ferrocene quencher and the naphthalimide fluorophore are linked by a disulfide bond, has been developed. This probe can be activated by GSH with fluorescence a turn-on response for blocking the PET process. In addition, it was successfully applied for distinguishing cancer cells from normal cells |
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Keywords: | GSH sensing Photoinduced electron transfer Fluorescent sensor Cancer cells imaging |
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