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Preparation of mesoporous silica nanoparticle with tunable pore diameters for encapsulating and slowly releasing eugenol
Authors:Tianlu Zhang  Zhiguo Lu  Jianze Wang  Jie Shen  Qiulian Hao  Yan Li  Jun Yang  Yunwei Niu  Zuobing Xiao  Lei Chen  Xin Zhang
Institution:1. State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China;2. Department of Obstetrics and Gynecology, Navy General Hospital of People Liberation Army, Beijing 100048, China;3. School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China;4. Shanghai Research Institute of Fragrance and Flavor Industry, Shanghai 200232, China;5. School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 200233, China
Abstract:Fragrances are frequently added to a variety of products, including food, cosmetics and health products. However, the high volatility and instability of essence limit its application in some fields. In this study, mesoporous silica nanoparticles (MSNs) were prepared to encapsulate eugenol, which could reduce the volatilization of the fragrance molecules. A facile approach was presented to synthesize MSNs with three different pore diameters for encapsulating eugenol. In addition, the properties of MSNs including mean particle size, morphology, encapsulating efficiency and release tendency were characterized. Results showed that the larger the pore diameters of MSNs, the more aromatic molecules were adsorbed. Furthermore, the release mechanism was described as the smaller the pore diameters of MSNs, the slower the release of eugenol.
Keywords:Eugenol  Mesoporous silica nanoparticles  Nano-fragrance  Slow release of fragrance
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