配糖蛋白B—阳离子丙烯酸树脂微胶囊的性能研究

本文研究了配糖蛋白B-阳离子丙烯酸树脂微胶囊的形态、粒径及粒径分布,并在模拟胃液的酸性缓冲液中进行了微胶囊的溶解释放试验。结果表明该微胶囊能溶于人体的胃液中,可配制适合儿童口服的混悬剂。

Study on Properites of Glycoprotein B-Cationic Acrylic Resin Microcapsules

The dissolution release test of three batches of glycoprotein B-Cationic acrylic resin microcapsules have been investigated at acidic buffer (pH = 1 and pH = 3). The size and size distribution of microcapsules were measured by photon correlation spectrograph method after freeze drying, The morphology of microcapsules was observed by Nikon microscope as well. The investigation results have shown that these microcapsiules can be dissolved and relesased completely and also indicate that the microcapsules could be formulated into an oral suspention dosage form for children.