| 正常人和结直肠癌患者血清的拉曼光谱探测与区别 |
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| 引用本文： | 李晓舟,杨天月. 正常人和结直肠癌患者血清的拉曼光谱探测与区别[J]. 光散射学报, 2011, 23(2): 138-141 |
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| 作者姓名： | 李晓舟 杨天月 |
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| 作者单位： | 1. 沈阳理工大学理学院,沈阳110159;大连理工大学物理与光电工程学院,大连116024
2. 沈阳理工大学理学院,沈阳,110159 |
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| 摘 要： | 本文对比分析了正常人和结直肠癌患者的血清的拉曼光谱.选择拉曼峰信息和荧光背景信息作为参数进行统计分析.用主成分回归(Principal component regression,PCR)和线性辨别分析(linear discriminant analysis,LDA)对所选参数进行分析以观察这些参数对光谱的代表性,得到...
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| 关 键 词： | 拉曼光谱 血清 结直肠癌 PCR LDA |
| 收稿时间： | 2011-01-25 |
Detection and Discrimination of Normal and Colorectal Cancer Serum using Raman Spectroscopy |
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| LI Xiao-zhou,YANG Tianyue. Detection and Discrimination of Normal and Colorectal Cancer Serum using Raman Spectroscopy[J]. Chinese Journal of Light Scattering, 2011, 23(2): 138-141 |
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| Authors: | LI Xiao-zhou YANG Tianyue |
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| Affiliation: | 1(1.School of Science,Shenyang Ligong University,Shenyang 1100159,China;2.School of Physics and Optoelectronic Engineering,Dalian University of Technology,Dalian 116024,China) |
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| Abstract: | Herein,Raman spectra of serum from normal people and colorectal cancer patients were compared and analyzed.The information of Raman peaks and that of the fluorescence background were selected as parameters for statistical analysis.Principal component regression(PCR) combinded with linear discriminant analysis(LDA) were used on the selected parameters to see the performance of the parameters,we got a diagnostic accuracy of 87.50%.The conclusion is that the selected parameters can maintain the information of original spectra well and Raman spectroscopy of serum has the potential for the diagnosis of colorectal cancer. |
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| Keywords: | Raman spectroscopy serum colorectal cancer PCR LDA |
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