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Regioselective synthesis and structural elucidation of 1,4-disubstituted 1,2,3-triazole derivatives using 1D and 2D NMR spectral techniques
Authors:Babu Thelagathoti Hari  Kumar B V N Phani  Rajeswari C  Perumal Paramasivan T
Affiliation:1. Organic Chemistry Division, Central Leather Research Institute, , Adyar, Chennai, 600 020 India;2. Chemical Physics Laboratory, Central Leather Research Institute, , Adyar, Chennai, 600 020 India
Abstract:Regioselective synthesis of 2-[1-(2-oxo-2-phenylethyl)-1H-[1,2,3]triazol-4-ylmethoxy]-benzaldehyde derivatives was achieved by [3 + 2] cycloaddition reaction of 2-(prop)-2-ynyloxy-benzaldehyde derivatives with phenacyl azide. The regiochemistry and the spectral assignments of the synthesized triazole derivatives were studied using both 1D and 2D NMR spectral techniques in solution.
Keywords:1H NMR  13C NMR  2D NMR  1,4‐disubstituted 1,2,3‐triazoles
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