Direct functionalisation of group 10 N-heterocyclic carbene complexes for diversity enhancement |
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| Authors: | Chardon Edith Puleo Gian Luigi Dahm Georges Guichard Gilles Bellemin-Laponnaz Stéphane |
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| Institution: | Institute of Physics and Chemistry of Materials of Strasbourg (IPCMS), University of Strasbourg - CNRS UMR7504, 23 rue du Loess, 67034 Strasbourg, France. |
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| Abstract: | The synthesis of alkyne-substituted N-heterocyclic carbene complexes of Pd(II) and Pt(II) is reported. Catalyzed 1,3-dipolar cycloaddition with azides has been applied as a modular way of functionalisation of group 10 transition metal NHC complexes to generate potentially new metallodrugs. |
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