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Microwave‐assisted synthesis of phenylenedi(4′,4“‐tetrahydroquinoline) and di(4′,4”‐tetrahydropyridine) derivatives
Authors:Shujiang Tu  Fang Fang  Songlei Zhu  Tuanjie Li  Xiaojing Zhang  Qiya Zhuang  Shuijun Ji  Yong Zhang
Abstract:The synthesis of bifunctional pyridine and quinolione derivatives were investigated using terephthalic and isophthalic aldehydes as a precursor. The reaction proceeds under microwave irradiation with good yield (70–92%) and short reaction time (7–9 min.). We provide a rapid and efficient method of synthesizing a range of bifunctional monocyclic and bicyclic products related to 1,4‐dihydropyridines (1,4‐DHPs).
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