| Abstract: | The model study on physico-chemical basis of the tentative mechanism of artificial immunogene action was undertaken. Monodisperse carboxylated polystyrene latex was used as model to investigate the following problems: reversibility of polycation adsorption on the negatively charged surface, migration of macromolecules between particles, adsorption of polycation in the presence of abundant proteins. Polycation was proven to adsorb reversibly and, despite its high affinity to the negatively charged surface, to pass from one disperse phase particle to another. Neither positively nor negatively charged proteins prove to hinder polycation adsorption on the surface. |
