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Synthetic Study of 4‐Substituted Piperidine Ring in Elarofiban,RWJ‐50042, Tirofiban and Paroxetine
Authors:Meng‐Yang Chang  John  Yi‐Chung Lin  Shui‐Tein Chen  Nein‐Chen Chang
Abstract:A new strategy for synthesizing a 4‐substituted piperidine ring uses the formal 3+3] cycloaddition reaction as the key protocol. This method provides a convenient formal synthesis of elarofiban, RWJ‐50042, tirofiban and paroxetine.
Keywords:Piperidine  Glutarimide  Elarofiban  RWJ‐50042  Tirofiban  Paroxetine  Femoxetine
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