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An efficient synthesis of chlorinated imidazoles through tert-butyldimethylsilyloxy derivatives |
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| Authors: | Genevi ve Estenne,Gr&#x rard Leclerc,Pierre Dodey,Patrice Renaut |
| Affiliation: | Geneviève Estenne,Gr̀rard Leclerc,Pierre Dodey,Patrice Renaut |
| Abstract: | The protection of 2-substituted imidazole-5-methanol derivatives by tert-BDMS allowed the chlorination of the heterocycle in position 4 with good yield whereas direct chlorination on the imidazole alcohol was unsuccessful. |
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