A new procedure for the synthesis of 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones |
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Authors: | C B Vicentini A C Veronese M Guarneri M Manfrini P Giori S Guccione |
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Abstract: | Thiation of N-(1-tert-butyl-3-methylpyrazol-5-yl)carboxamides 2 with the Lawesson reagent afforded the corresponding thiocarboxamides 3 . Heating of 3 in formic acid gave the N-dealkylated thiocarboxamides 4 which were cyclized into 4H-pyrazolo1,5-c]1,3,5]thiadiazine-4-thiones 5 by treatment with thiophosgene. |
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