C-H bond functionalization in the synthesis of fused 1,2,3-triazoles |
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Authors: | Panteleev Jane Geyer Karolin Aguilar-Aguilar Angelica Wang Letian Lautens Mark |
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Institution: | Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada. |
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Abstract: | A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields. |
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