Novel isocyanide-based three-component synthesis of 3,4-dihydroquinoxalin-2-amine derivatives |
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| Authors: | Shaabani Ahmad Maleki Ali Mofakham Hamid Khavasi Hamid Reza |
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| Institution: | Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran. ashaabani@cc.sbu.ac.ir |
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| Abstract: | Synthesis of a novel class of highly substituted 3,4-dihydroquinoxalin-2-amine derivatives including spirocyclic compounds from three-component condensation reaction of o-phenylenediamines, diverse carbonyl compounds, and isocyanides in the presence of a catalytic amount of p-toluenesulfonic acid in good to excellent yields at room temperature is described. |
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