Synthesis and biological activity of certain amino-derivatives of 5α-steroids |
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| Authors: | M I Merlani L Sh Amiranashvili K G Mulkidzhanyan E P Kemertelidze |
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| Institution: | (1) I. G. Kutateladze Institute of Pharmaceutical Chemistry, Academy of Sciences of Georgia, Tbilisi, 0159, ul. P. Saradzhishvili, 36 |
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| Abstract: | Certain 17β-aminoderivatives of 5α-steroids based on tigogenin were synthesized and their antitumor activity was studied. The structures of the synthesized
compounds were confirmed by NMR and IR spectroscopy and mass spectrometry.
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Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 263–265, May–June, 2006. |
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| Keywords: | aminosteroids antitumor activity |
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