Three-component one-pot synthesis of 4,6-diarylpyrimidin- 2(1H)-ones under solvent-free conditions in the presence of sulfamic acid as a green and reusable catalyst |
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| Authors: | Majid M. Heravi Leila Ranjbar Fatemeh Derikvand Behnoush Alimadadi |
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| Affiliation: | Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran. mmh1331@yahoo.com |
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| Abstract: | A rapid and efficient one-pot method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones and related heterocycles is described. The condensation of acetophenone derivatives, aldehydes and urea in the presence of sulfamic acid was employed to synthesize a variety of pyrimidinones in moderate to excellent yields. The scope and limitations of this method are described. |
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