Production possibility of 61Cu using proton induced nuclear reactions on zinc for PET studies |
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| Authors: | F. Szelecsényi Z. Kovács K. Suzuki K. Okada T. N. van der Walt G. F. Steyn S. Mukherjee |
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| Affiliation: | (1) Cyclotron Department, Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), H-4026, Bem tér 18/C, Debrecen, Hungary;(2) Cyclotron Department, Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), H-4026, Bem tér 18/C, Debrecen, Hungary;(3) Radiopharmaceutical Chemistry Section, Department of Medical Imaging, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan;(4) Radiopharmaceutical Chemistry Section, Department of Medical Imaging, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan;(5) Radionuclide Production Group, iThemba Laboratory for Accelerator Based Sciences, Somerset West, 7129, South Africa;(6) Radionuclide Production Group, iThemba Laboratory for Accelerator Based Sciences, Somerset West, 7129, South Africa;(7) School of Studies in Physics, Vikram University, Ujjain, 456010, India |
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| Abstract: | Summary Excitation functions were measured by stacked-foil technique for the natZn(p,x)61Cu, 66Zn(p,x)61Cu, 68Zn(p,x)61Cu and natZn(p,x)60Cu nuclear processes up to 100 MeV. The experimental cross sections were compared with published data. On the base of these excitation functions, the cross sections of 64Zn(p,x)61Cu process were also deduced. Integral thick target yields were calculated for the 64Zn(p,x)61Cu and nat,64Zn(p,x)60Cu processes and irradiation parameters were elaborated for the 61Cu production via the 64Zn+p reactions for low and middle energy accelerators. According to our calculations the yield of 61Cu amounts to 1.02 . 1011 Bq . A-1 . s-1 (9.9 mCi .µ A-1 . h-1) from 19®10 MeV while it reaches 3.91 . 1011 Bq . A-1 . s-1 (38 mCi . µ A-1 . h-1) in the energy range of 67®60 MeV. |
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