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Modular synthesis of isoxazolopyridones and pyrazolopyridones |
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| Authors: | Mauro F.A. Adamo Eleanor F. Duffy Piero Sarti-Fantoni |
| Affiliation: | a Centre for Synthesis and Chemical Biology (CSCB), Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland b Dipartimento di Chimica, Università di Siena, Via Aldo Moro, Siena 53100, Italy c Dipartimento di Chimica Organica ‘U. Schiff’, Università di Firenze, Via della Lastruccia, Sesto Fiorentino 50019, Italy |
| Abstract: | Herein we described the preparation of two novel heterocyclic nuclei isoxazolopyridone and pyrazolopyridone. The syntheses are modular in nature and fast to execute. The title compounds were obtained pure without intervention of chromatography. |
| Keywords: | Fused isoxazoles Polyfunctional scaffold Fused pyrazoles |
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