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Novel steroids from the soft coral Nephthea chabrolii |
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| Authors: | Jui-Hsin Su Ho-Cheng Huang Yang-Chang Wu Chi-Hsin Hsu Jyh-Horng Sheu |
| Affiliation: | a Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan b Department of Chemical Engineering, Cheng Shiu University, Kaohsiung 833, Taiwan c Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan d Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan e Faculty of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan f Asian Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan |
| Abstract: | Three new metabolites including two new steroids, chabrolosteroids A and B (1 and 2), and a novel spirosteroid chabrolosteroid C (3), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of these metabolites were elucidated by extensive spectroscopic analysis and by comparison of the spectral data with those of related steroids. This is the first report of a steroid with a spiro-ring A, B system in natural products. |
| Keywords: | Chabrolosteroids Spirosteroid Nephthea chabrolii |
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