1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-promoted efficient and versatile aza-Michael addition |
| |
| Authors: | Chang-Eun Yeom |
| |
| Institution: | Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, 151-747, Republic of Korea |
| |
| Abstract: | A convenient and versatile method was developed for aza-Michael addition using a substoichiometric amount of 1,8-diazabicyclo5.4.0]undec-7-ene (DBU). Various nitrogen nucleophiles were efficiently introduced to α,β-unsaturated carbonyl compounds employing 0.5 equiv of DBU. Furthermore, other heteroatomic nucleophiles could also be introduced successfully under the same reaction conditions. |
| |
| Keywords: | Aza-Michael DBU Catalytic Nitrogen nucleophiles Conjugate addition |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
