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Modular syntheses of isoxazoloazepinones and pyrazoloazepinones |
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| Authors: | Mauro FA Adamo Eleanor F Duffy Piero Sarti-Fantoni |
| Institution: | a Centre for Synthesis and Chemical Biology (CSCB), Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland b Dipartimento di Chimica, Università di Siena, Via Aldo Moro, Siena 53100, Italy c Dipartimento di Chimica Organica ‘U. Schiff’, Università di Firenze, Via della Lastruccia, Sesto Fiorentino 50019, Italy |
| Abstract: | Herein we described an optimised synthesis of isoxazoloazepinone and novel heterocycle pyrazoloazepinone. These syntheses are modular in nature and fast to execute. The title compounds were obtained pure without the intervention of chromatography. |
| Keywords: | Fused isoxazoles Polyfunctional scaffold Fused pyrazoles |
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