Quinazolines. 3*. synthesis of 6-bromo-8-chloro-sulfonylquinazoline-2,4(1h,3h)-dione and its interaction with nucleophilic reagents期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

按检索

*Quinazolines. 3. synthesis of 6-bromo-8-chloro-sulfonylquinazoline-2,4(1h,3h)-dione and its interaction with nucleophilic reagents**

Authors:	R Sh Kuryazov N S Mukhamedov D A Dushamov R Ya Okmanov Kh M Shakhidoyatov B Tashkhodzaev

Institution:	(1) S. Yu. Yunusov Institute of Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, 100170, Uzbekistan;

Abstract:	6-Bromo-8-chlorosulfonylquinazoline-2,4(1H,3H)-dione was obtained from 6-bromoquinazoline-2,4(1H,3H)-dione and chlorosulfonic acid in place of the expected 6-bromo-7-chlorosulfonyl-quinazoline-2,4(1H,3H)-dione. Interaction of the product with water, alcohols, ammonia, aliphatic and heterocyclic amines gave 6-bromo-8X-quinazoline-2,4(1H,3H)-diones (X = SO₂OH, SO₂OAlk, SO₂NR¹R²), and, by reduction with SnCl₂·2H₂O in hydrochloric acid, 6-bromo-8-mercaptoquinazoline-2,4-dione was obtained.

Keywords:
本文献已被 SpringerLink 等数据库收录！