A Novel Stereoselective Synthesis of 8-O-4' Neolignans |
| |
| Authors: | Xiao Chuan CHEN Wen Xin GU Xiao Bi JING Xin Fu PAN |
| |
| Institution: | Xiao Chuan CHEN,Wen Xin GU,Xiao Bi JING,Xin Fu PAN* Department of Chemistry,National Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000 |
| |
| Abstract: | 1-(4-hydroxy-3-methoxyphenyl)-2-(4-formyl-2-methoxyphenoxy)-propane-1,3-diol, A 8-O-4' neolignan, has been stereoselectively synthesized in eight steps from ferulic acid, and the directly cis opening of epoxide in epoxidation and Mitsunobu reaction were used ingeniously as two key steps with high stereoselectivity. |
| |
| Keywords: | 8-O-4' Neolignans ferulic acid addition Mitsunobu reaction stereoselective synthesis |
| 本文献已被 CNKI 等数据库收录！ |
|
