Quinazolines. 2*. unsymmetric 1,3-dialkyl-6-chlorosulfonyl- quinazoline-2,4-diones in nucleo- philic substitution reactions |
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| Authors: | R. Sh. Kuryazov N. S. Mukhamedov Kh. M. Shakhidoyatov |
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| Affiliation: | (1) S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of Uzbekistan, Tashkent, 100170, Uzbekistan; |
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| Abstract: | The corresponding 6-chlorosulfonylquinazoline-2,4-diones were synthesized by the reactions of 1-methylquinazoline-2,4-dione and its 3-alkyl-substituted derivatives with chlorosulfonic acid. Treatment of the products with nucleophilic agents (water or ammonia, aliphatic and cyclic amines) gave 2,4-dioxoquinazolin-6-sulfonic acids or their amides. |
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