| Abstract: | The readily available sulfolenes can be used as the 1-carbanion equivalent of the unsubstituted and substituted buta-1,3-dienes which can be directly alkylated. This convenient synthetic method is not only regiospecific, efficient and straight forward, but also favorable because the normally unstable molecules containing conjugated dienyl moiety can be prepared directly in their protected forms. The deprotection step is both clean and highly stereoselective. The applications of this type of reaction in organic synthesis include the trans-β-ocimene, α-farnesene and a series of hydroindans and hydronaphthalenes. |
